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Positive Results for Edoxaban in VTE/PE

Findings from the Hokusai-VTE trial of edoxabanThe post Positive Results for Edoxaban in VTE/PE appeared first on CardioExchange.

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Is Edoxaban the Most Promising of the Novel Anticoagulants?

Samuel Z. Goldhaber offers his perspective on the Hokusai-VTE randomized trial comparing edoxaban and warfarin in patients with symptomatic venous thromboembolism. The post Is Edoxaban the Most...

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Is It Safe to Treat Acute Pulmonary Embolism in an Outpatient Setting?

Christopher Kabrhel discusses his research group’s study of the factors associated with clinical deterioration and the need for hospital-based interventions after an acute pulmonary embolism. The post...

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New Trial Confirms Role for Dabigatran in Venous Thromboembolism

A new study helps support a role for  the new oral anticoagulant dabigatran (Pradaxa, Boehringer Ingelheim) in patients with venous thrombosis (VTE).  The RE-COVER II trial, published online in...

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Vena Cava Filters Reduce Pulmonary Emboli But Increase VTE Recurrence Tenfold

Inferior vena cava filters seem to offer protection against death from pulmonary embolism when compared with anticoagulant therapy, but they have no significant effect on all-cause mortality. In...

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Pulmonary Embolism in a Patient with Acute Decompensated Systolic Heart Failure

Ian Neeland presents our latest case: A 42-year-old man with heart failure is found to have a large pulmonary embolus. Tell us how you'd manage his treatment. The post Pulmonary Embolism in a Patient...

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Selections from Richard Lehman’s Literature Review: March 24th

This week's topics include non-leg venous thrombosis in critically ill adults, a comparison of factor Xa inhibitors and warfarin for preventing stroke and thromboembolism in atrial fibrillation, and...

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Selections from Richard Lehman’s Literature Review: April 14th

This week's topics include TOPCAT, fibrinolysis for those with intermediate-risk PE, and more.The post Selections from Richard Lehman’s Literature Review: April 14th appeared first on CardioExchange.

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Mixed Results for Thrombolysis in Pulmonary Embolism

  The role of thrombolytic therapy for the treatment of pulmonary embolism has been unclear, as it has been difficult to measure the precise balance between enhanced clot-dissolving efficacy and...

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A Meta-Look at Thrombolysis vs. Conventional Anticoagulation for PE

Jay Giri and Saurav Chatterjee discuss their meta-analysis of trials comparing thrombolytic therapy and conventional anticoagulation in patients at intermediate risk for pulmonary embolism. The post A...

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